Wnt/β-catenin signaling in hepatic organogenesis
نویسندگان
چکیده
منابع مشابه
β-catenin is overexpressed in hepatic fibrosis and blockage of Wnt/β-catenin signaling inhibits hepatic stellate cell activation
β-catenin, a core component of Wnt/β-catenin signaling, has been shown to be an important regulator of cellular proliferation and differentiation. Abnormal activation of Wnt/β-catenin signaling promotes tissue fibrogenesis. In the present study, the role of β-catenin during liver fibrogenesis was analyzed and the functional effects of β-catenin gene silencing in hepatic stellate cells (HSCs) us...
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ژورنال
عنوان ژورنال: Organogenesis
سال: 2008
ISSN: 1547-6278,1555-8592
DOI: 10.4161/org.4.2.5855